Prolotherapy (prolozone therapy) has been used for decades, mostly as a treatment for musculoskeletal pain arising from ligamentous laxity. Loose ligaments can result from overuse or injury. They can be pain generators by themselves or they can cause joint cartilage to wear out faster than it can be replaced. Various injectables have been used over the years to trigger proliferation of ligamentous tissue, but the needle trauma itself may be the primary driver. When ozone gas is used as an injectable the procedure is usually called prolozone. Although a head-to-head study has yet to be done we feel that ozone is both safer and more effective than many other injectables commonly used by prolotherapists. Dr. Shawn Naylor has also has found prolozone to be a more effective and affordable than the more well known PRP (plasma rich protein) joint injections.
The cost is $100 per injection + office visit with the practitioner. (Denver)
Injection therapies are frequently utilized to treat conditions involving musculoskeletal injury, dysfunction and pain. It’s difficult to accurately predict how effective they will be: some patients who look like great candidates get no benefit at all; sometimes what seems like a ‘Hail Mary’ turns out to be a cure. Some patients see improvement only after the 6-8w inflammatory response to a prolotherapy injection has run its course. Some patients come every 6-12m for maintenance therapy. Most prolotherapists report that 60-70% of their patients respond to treatment.
Refer to American Academy of Ozonotherapy (aaot.org) for more info.