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LDA Therapy

LDA therapy is ‘Low Dose Antigen’ therapy. It is an injection therapy used to treat various symptoms caused by allergic reactions. LDA treatment focuses on decreasing allergies (the immune system overreaction) to substances and decreasing symptoms such as eczema, gut irritation, fatigue and joint discomfort.

LDA Therapy

$280/injection + office visit. (Louisville and Denver Locations with Mike Kehoe, PA-C)

How does LDA Work?
LDA stands for ‘Low Dose Antigen’ therapy. Compared to conventional ‘allergy shots,’ LDA may be a safer and more effective form of immunotherapy for most patients. When you have allergies, your immune system is ‘over-reacting’ – treating something like pollen as if were dangerous bacteria. This causes unpleasant symptoms. White blood cells called T helper cells tell the immune system to react more to a particular ‘antigen,’ like food or an inhalant such as dust, dander, mold, pollen or chemicals. T regulator cells tell the body to react less. LDA treatment programs immature T cells to become regulator rather than helper cells by exposing them to very precise doses of the allergens (antigens) in question.

How often does a person need to have treatments?
A person with relatively simple allergies, like hay fever, typically requires two LDA shots first year, then one a year after that. Patients with more complex medical problems usually need a shot every 2 months the first year, every 3-4 months the second year, and 2-3 per year after that. After two years, many patients can get by on a single LDA shot twice a year or less.

Will my health insurance carrier cover LDA?
The office visit is billable to insurance. The injection procedure and the medication itself are $280 per injection and are not billable to, or recoverable from, any major commercial or government insurance carriers. Neither Mike Kehoe, PA-C nor the Sound Clinic make any claims about the degree to which funds may be recovered for the in-person office visits; insurance coverage in recent years has trended sharply in the direction of higher deductibles and lower or non-existent out-of-network coverage.

How quickly does LDA provide relief?
Response varies with the age and health of the patient. It is not unusual for younger patients to experience relief from symptoms more rapidly after having an LDA injection. However, the primary effect of the treatment occurs about three weeks after the LDA injection. Many patients feel some degree of relief after the first injection but the duration of the response will vary from patient to patient. Most patients report relief from symptoms by the third injection with enhanced and extended relief following each subsequent treatment.

How safe is LDA?
Even after tens of thousands of treatments there have been no fatal reactions to LDA injections. This is a much better safety record compared to traditional allergy shots. The very highest possible dose of LDA (some LDA antigens are lower) is at least a million times less than the standard dose for conventional immunotherapy. A small number of patients have experienced asthma exacerbations. If you have been diagnosed with asthma or have a history of intermittent wheezing or chest tightness, please be sure to mention this in your initial visit. Careful avoidance of triggers and/or complicated pre-treatment protocols is necessary in some cases. Failure to adhere to these recommendations increases the probability of adverse reactions and decreases the probability of effective treatment.

What kind of local reactions may occur with an LDA injection?
Most patients will experience a localized swelling at the site of the LDA injection. This is actually a positive sign that the treatment is working and engaging the immune system response. There may also be some itching and redness. Rarely, there is swelling of the lower arm following the treatment which is a temporary reaction.

What kinds of Diseases has LDA helped?
Physicians have used LDA for a very wide range of problems. A 1990s study involving more than 10,000 patients was done in the United States with data on 50 diseases and symptoms. Listed here are conditions with more than 100 patients treated. Half or greater improvement in frequency of symptoms is shown. Improvement in severity is quite similar.

Repeated Ear Infections 89% Repeated Chest Infections 81%
AngioEdema 78% Asthma, Seasonal 79%
Seasonal Rhinitis (Hay Fever) 77% Chronic Cough, not asthma 77%
Chronic Sinusitis 70% Asthma, perennial (year around) 75%
Allergic Conjunctivitis 77% Nasal Polyps 74%
Perennial Rhinitis 74% Contact Dermatitis 75%
Headaches, Not Migraine 75% Eczema 69%
Migraine/Severe Headache 68% Chronic Fatigue 64%
Brain Fog/Mental Confusion 68% CFIDS 64%
Depression 62% Candida Related Complex 68%
Arthritis, Non-specific 61% Food Allergy, Immediate 72%
Autism 53% Food Allergy, Other 72%
Hyperactivity 68% Chemical Sensitivity 65%
Emotional/Behavioral Problems 69% Irritable Bowel 69%

Results for less commonly seen conditions are found on under “EPD & LDA, then “ EPD Study Results.”

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